Products
ANGPTL4 antibody
Category:
Research Area:
Synonyms: | Angiopoietin like 4 antibody, Angiopoietin like protein 4 antibody, Angiopoietin related protein 4 antibody, ANGPTL2 antibody, ANGPTL4 antibody, ARP4 antibody, FIAF antibody, HFARP antibody, NL2 antibody, PGAR antibody, pp1158 antibody, PSEC0166 antibody, UNQ171/PRO197 antibody | ||
Catalogue No.: | FNab00399 | Reactivity: | Human, Mouse |
Host: | Rabbit | Tested Application: | ELISA, IHC, IF, IP, WB |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- Product Name
- ANGPTL4 antibody
- Catalogue No.
- FNab00399
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- angiopoietin-like 4
- Alternative Names
- Angiopoietin like 4 antibody, Angiopoietin like protein 4 antibody, Angiopoietin related protein 4 antibody, ANGPTL2 antibody, ANGPTL4 antibody, ARP4 antibody, FIAF antibody, HFARP antibody, NL2 antibody, PGAR antibody, pp1158 antibody, PSEC0166 antibody, UNQ171/PRO197 antibody
- UniProt ID
- Q9BY76
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, IHC, IF, IP, WB
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00399(ANGPTL4 Antibody) at dilution of 1:1000
IP Result of anti-ANGPTL4 (IP:FNab00399, 4ug; Detection:FNab00399 1:500) with mouse heart tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney slide using FNab00399(ANGPTL4 Antibody) at dilution of 1:50
Immunofluorescent analysis of ( -20°C Ethanol) fixed HEK-293 cells using FNab00399 (ANGPTL4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity).